The challenges of solid oral forms formulation
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چکیده
Piero Iamartino coordinates the new AFI’s Pharmaceutical Technology working group, together with professor Andrea Gazzaniga of the University of Milan. He summarizes for Pharma World the history and final goals of the MCS initiative, originally proposed in 2014 by a British university-industry mixed working group led by representatives of three big pharma, Bristol-Myers Squibb, GlaxoSmithKline and AstraZeneca. AFI’s Pharmaceutical Technology group accepted the invitation of the authors of the paper published in Pharmaceutical Development and Technology aimed to review the potential of the proposed approach and how it could benefit the pharmaceutical industry.
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Enhancement of Oral Bioavailability and Solid Dispersion: A Review
Improving oral bioavailability of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility problems. Most of the newly invented chemical entities are poorly water soluble. As a result formulating them as oral solid dosage forms is a hurdle to the specialists. Many techniques have been exercised to improve oral bioavailability of drugs. Among s...
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